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Magicplex™ VanR Real-time TestSimultaneous detection of vanA, vanB, and vanC genes Seegene's Magicplex™ VanR Real-time Test has been notified at Germany CA (Competent Authorities). The CE mark will allow more opportunities for Seegene to market and sell within the European Union.
Oct 15, 2010｜ Magicplex VanR Real-Time Test
Anyplex™ VanR Real-Time detection Simultaneous detection of vanA, vanB, and vanC geneEnterococci are the major cause of surgical-site infections and the third leading cause of urinary tract and bloodstream infections. Vancomycin is an antibiotic that is often used to treat infections caused by these Enterococci. In some instances, Enterococci become resistant to this drug and thus are called vancomycin-resistant Enterococci (VRE). Most VRE infections occur in hospitals. Vancomycin-resistant Enterococci (VRE) are now an increasingly important problem in hospitals worldwide. Both vanA and vanB genes are transferable and can spread from organism to organism. For this reason, an accurate detection is necessary in order to separate the carriers from patients. On the other hand, vanC genes are not transferable and less significant clinically, and moreover they do not require carriers to be secluded. However, the detection of vanC is still important for discrimination of VRE with acquired resistance as well as for preventing unnecessary procedures for infection management.
Feb 01, 2010｜ Anyplex™ VanR Real-time Detection
Magicplex™ VanR Real-Time Detection Simultaneous detection of vanA, vanB, and vanC genes The importance of testing for VRE VRE (vancomycin-resistant enterococci) are an important category of opportunistic pathogenic bacteria, the occurrence of which has risen in frequency worldwide with the increase in the use of vancomycin. As most VRE display resistance to multiple drugs, they are difficult to treat. In addition, their resistant characteristics may be passed on to other opportunistic pathogenic bacteria, such as the Staphylococcus aureus, which can be highly problematic. Therefore, in order to prevent the spread of VRE in the hospital, conducting a test for VRE quickly and accurately is essential. Vancomycin resistance genotyping vanA and vanB genes are transferable and can spread from organism to organism. So, accurate detection is required in order to separate the carriers from patients. vanC genes are not transferable and have little clinical importance, and do not require the carrier to be secluded. The detection of vanC is necessary for discriminating VRE with acquired resistance, and for preventing unnecessary infection management procedures. VRE diagnostic methods Disk diffusion test and automated systems, such as the Vitek system or the Microscan, have high accuracy and reliability. These methods, however, are able to only test for phenotypes, and cannot determine the exact genotypes. Moreover, as there have been reports of VRE which has incongruent genotypes against its phenotypes, a molecular biological test is necessary in order to identify resistant genotypes.
Jan 01, 2010｜ Magicplex VanR Real-Time Detection
Seeplex® UTI ACE Detection Detection of bacteria causing urinary tract infection Launched Seeplex® UTI ACE Detection Seeplex® MRSA ACE Detection Detection of MRSA (methicillin resistant Staphylococcus aureus) Launched Seeplex® MRSA ACE Detection Seeplex® GBS-R ACE Detection Detections of GBS and erythromycin/clindamycin resistant genes Launched Seeplex® GBS-R ACE Detection.
Jun 01, 2009｜ Seeplex® GBS-R ACE Detection
Detection of vanA & vanB genes which cause vancomycin-resistanceSeeplex® VRE ACE Detection detects the vanA and vanB genes which cause vancomycin-resistance in enterococci isolated from stool culture in a single test. The Seeplex® VRE ACE Detection detects the vanA and vanB genes which cause vancomycin-resistance in enterococci isolated from stool culture in a single test.Enterococci are normally indigenous bacteria found in the GI tract and female genitals, but recently they were recognized as major pathogens causing urinary tract infections and sepsis by nosocomial infection. Vancomycin, which is used in the treatment of enterococci infection, is a drug that has an antibacterial effect by forming a complex with the D-alanyl-D-alanine terminal of the peptidoglycan precursor to block transglycosylation and transpeptidation during the synthesis of the cell wall of Gram-positive cocci. However, vancomycin-resistant enterococci (VRE) tend to multiply rapidly due to the high frequency and continuous use of vancomycin. The Seeplex® VRE ACE Detection is a PCR method that incorporates DPO technology with high sensitivity and specificity, and is a product that can test for the vancomycin- resistant vanA gene and the vanB gene of enterococci in one test.
Mar 03, 2008｜ Seeplex® VRE ACE Detection